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Song Ling, Ph.D.
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Faculty Appointment:
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Research Investigator,
Department of Internal Medicine
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Specialty:
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Rheumatology
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Research Interests:
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1. The term of Rheumatoid Arthritis (RA) literally means "joint inflammation". Our lab identified one of the inflammation factor-Nitric Oxide could be stimulated by RA shared epitope. In ex-vivo study, excessive DNA damage also has been observed after shared epitope treatment. Further study on downstream of Nitric Oxide signal is in process.
2. Our labor identified the receptor of shared epitope. The kinetic and affinity analysis of shared epitope binding with its receptor, and potential inhibitor for this interaction have been assessed by Surface Plasmon Resonance technique. Further study on identifying residues involved in this interaction will be performed in bioinformatics and biophysical approach.
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Degree:
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Ph.D., 1998, Shanghai Institute of Biochemistry, Chinese Academy of Sciences
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Fellowships:
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Postdoctoral Research Fellowship, Pathology,
2000, Wayne State University
Postdoctoral Research Fellowship, Rheumatology,
2002, University of Michigan
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Faculty Appointment Date:
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7/1/2002
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Academic office address
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Medical Science Research Building I
1150 West Medical Center Drive
Room 5514
Ann Arbor, MI 48109-5680
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Academic office telephone:
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(734)936-7905
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Academic office FAX:
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(734)763-4151
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