Andrea Todisco, M.D.
Faculty Appointment:	Associate Professor, Department of Internal Medicine
Specialty:	Gastroenterology
Clinical Interests:	Peptic ulcer disease. Gastric acid secretion.
Research Interests:	Dr. Todisco's research efforts have been focused on the investigation of the mechanisms that regulate epithelial cell growth and differentiation in the upper gastrointestinal tract. In particular, he has investigated the intracellular signal transduction pathways that mediate the multiple, complex actions of growth factors, such as gastrin and epidermal growth factor, in the stomach. Most of his work has been focused on the gastric parietal cells, highly specialized gastric epithelial cells that appear to play an important role in the complex process of differentiation and development of multiple cell lineages in the stomach. In a series of recent investigations Dr. Todisco has demonstrated that while protein kinase B/Akt is a crucial molecular switch for the induction and the maintenance of parietal cell differentiation, MAPK appears to be responsible for the activation of programs that lead to parietal cell dedifferentiation.
Degree:	M.D., 1985, University of Rome
Residency:	1986-1989, Henry Ford Hospital
Fellowship:	Gastroenterology, 1992, University of Michigan
Certifications:	1989, Internal Medicine 1991, Gastroenterology
Faculty Appointment Date:	6/5/1992
Academic office address	Medical Science Research Building I 1150 West Medical Center Drive Room 6510 Ann Arbor, MI 48109-0682
Academic office telephone:	(734)647-2942
Academic office FAX:	(734)763-2535
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