Raymond Yung, M.B.,Ch.B.
Faculty Appointment:	Professor, Department of Internal Medicine
Additional Titles:	Chief, Division of Geriatric and Palliative Medicine Co-Director, Geriatrics Center Associate Director of Research, Geriatric Research, Education and Clinical Center at VA Ann Arbor Healthcare System
Specialty:	Geriatric Medicine (Internal Medicine) Rheumatology and Geriatric Medicine
Clinical Interests:	Rheumatology, arthritis, immunology and geriatrics.
Research Interests:	Dr. Yung's research focuses on understanding the relationship between immune senescence and the development of immune and inflammatory diseases in the elderly. Aging represents a state of low grade inflammation. Dr. Yung has shown that upregulation of T cell chemokine response occurs in aging animals and humans. The epigenetic `drift' that occurs with aging may be involved in the deregulation of the chemokine system in aging. Dr. Yung is also investigating the effect of aging on dendritic cell function. Using a murine melanoma cancer model, he showed that `old' dendritic cells (DCs) are much less effective than their younger cohort as an immunotherapeutic agent. This is linked to the impaired ability of DCs to ingest antigen and to stimulate T cells. These findings may help to explain why elderly patients are at risk for a multitude of immune/inflammatory diseases.
Degree:	M.B.,Ch.B., 1986, University of Liverpool, England
Residency:	1988-1991, Sinai Hospital
Fellowships:	Rheumatology, 1994, Univ of Michigan Geriatric Medicine (Internal Medicine), 1996, Univ of Michigan
Certifications:	1991, Internal Medicine 1994, Rheumatology 1998, Geriatric Medicine
Faculty Appointment Date:	1/30/1995
Academic office address	East Ann Arbor Health and Geriatrics Center 4260 Plymouth Road Ann Arbor, MI 48109-5796-5796
Academic office telephone:	(734)764-6831
E-mail Address:	ryung@umich.edu
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