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Staff Appointment:
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Professor,
Department of Anesthesiology
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| Research Interests: |
There is a strong statistical association between low aerobic capacity disease risks and mortality. In 1996 we started artificial selection in rats for low and high aerobic capacity. We tested the hypothesis that artificial selection for low aerobic capacity would produce rats with high disease risk and that selection for high aerobic would produce rats resistant to the development of disease. By 10 generations of selection the low and high lines divided for many health risks that include features of the metabolic syndrome. We will use these rats to resolve the genotype to phenotype origin of complex disease. |
Education and Credentialing: |
| Degree: |
Ph.D., 1978, Texas Tech University School of Medicine
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| Fellowship: |
Cardiovascular Disease,
1981, Mayo Clinic
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