Andrea Todisco, M.D.

Faculty Appointment:	Associate Professor, Department of Internal Medicine
Specialty:	Internal Medicine
Clinical Interests:	Peptic ulcer disease. Gastric acid secretion.
Research Interests:	Dr. Todisco's research efforts have been focused on the investigation of the mechanisms that regulate epithelial cell growth and differentiation in the upper gastrointestinal tract. In particular, he has investigated the intracellular signal transduction pathways that mediate the multiple, complex actions of growth factors, such as gastrin and epidermal growth factor, in the stomach. Most of his work has been focused on the gastric parietal cells, highly specialized gastric epithelial cells that appear to play an important role in the complex process of differentiation and development of multiple cell lineages in the stomach. In a series of recent investigations Dr. Todisco has demonstrated that while protein kinase B/Akt is a crucial molecular switch for the induction and the maintenance of parietal cell differentiation, MAPK appears to be responsible for the activation of programs that lead to parietal cell dedifferentiation.

The following service(s) provide appointments by physician or self-referral:

Service Name	Location	Appointment Number
Gastroenterology	A. Alfred Taubman Health Care Center	(734) 647-5944 or 1-888-229-7408
Gastroenterology Specialty Clinics	Digestive Health Center - University Hospital	(734) 936-9250

Academic Office Address:

Medical Science Research Building I
1150 West Medical Center Drive
Room 6510
Ann Arbor, MI 48109-0682

Academic Office Telephone:

(734) 647-5944

Academic Office FAX:

(734) 763-7834

Education and Credentialing:
	Degree(s):	M.D., 1985, University of Rome
	Residency:	1986-1989, Henry Ford Hospital
	Fellowship:	Gastroenterology, 1992, University of Michigan
	Certifications:	1989, Internal Medicine 1991, Gastroenterology
	Faculty Appointment Date:	06/05/1992

Other Resources:
	Division Web site

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