|December 22, 2010||Media contact: Nicole Fawcett
U-M Cancer Center gets $10.7M grant to study colon, pancreas cancers
ANN ARBOR, Mich. — The University of Michigan Comprehensive Cancer Center has received a five-year $10.7 million grant from the National Cancer Institute to study colorectal and pancreatic cancer.
- Preventing colorectal cancer. Researchers will study whether substituting omega-3 fatty acids for omega-6 fatty acids could help prevent colorectal cancer. Omega-3 fatty acids are found in fish and are believed to improve heart health.
- Early detection of pancreatic cancer. Researchers will look for markers found in blood and plasma that are associated with pancreatic cancer. By using proteomics technology, researchers will analyze the changes in proteins in people with pancreatic cancer, non-cancerous pancreatic conditions and healthy pancreases. They hope to identify a marker or panel of markers that could be used to detect pancreatic cancer before it spreads to the rest of the body.
- Improving pancreatic cancer treatment. Researchers will look at whether blocking a certain protein could make pancreas tumors more sensitive to chemotherapy and radiation therapy. By doing this, researchers hope to improve the effectiveness of current treatments.
- Developing new pancreatic cancer treatments. Most pancreatic cancers express a gene called ATDC. Researchers will look at new therapies designed to target ATDC as a way of treating pancreatic cancer.